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SpinDistribute.com Article Directory

The following article was published in our article directory on April 7, 2022.
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Creative Biolabs' Innovative Solutions Power Macrophages Entering CAR Immunotherapy

Article Category: Business

Author Name: Candy Swift

Creative Biolabs has added a new line of CAR-macrophage therapeutic development services for clients all around the world as part of its unwavering commitment to biotechnology research.

For several years, chimeric antigen receptor (CAR) T cell therapy has been a hot issue in tumor treatment, and since it faces obstacles in solid tumors, CAR macrophage therapy has emerged as a new therapy aimed at enhancing CAR cells' capacity to target solid tumors.
Creative Biolabs has amassed a variety of knowledge in TCR and CAR-T&NK cell immunotherapy development over the years, and has established an unrivaled CAR design and construction platform across four CAR generations. It now offers the industry-leading Chimeric Antigen Receptor Macrophage (CAR-MA) services for solid tumor therapy to a worldwide reach.

·CAR Design & Construction

Creative Biolabs has designed a novel macrophage gene transfer strategy to overcome the gene engineering challenges of employing macrophages in adoptive cell treatments, which makes CAR-MA gain a desired anti-tumor phenotype as well as resistance to tumor-induced subversion.

·CAR-MA Preparation Service

Supported by a wealth of experience in choosing virus vectors with fine-tuning and molecular adjustments, Creative Biolabs offers reliable sources of macrophages, covering induced pluripotent stem cells (iPSC), human monocytic cell line (THP-1), human primary macrophages (CD14+ peripheral blood), and murine macrophages (Raw264.7, J774A.1).

·Macrophages Activation and Expansion Service

The scientist team is fully aware of the complex macrophage activation process, involving the coordinate/synergistic action of signals from cytokines, chemokines, and pathogen-associated molecular patterns (PAMPs), and is dedicated to providing innovative solutions for CAR-MA activation and expansion to advance the development of CAR-MA-based immunotherapies.

"Based on current research, CAR-macrophage therapy remains very promising in solid tumor treatment, and our mission is clear, to offer great products and great service to support your pursuit of a healthier world," as introduced by a senior scientist at Creative Biolabs.

Apart from the aforementioned services, the whole pipeline of CAR-MA services also includes target identification & selection, high-affinity antigen binder generation, in vitro assessments, and preclinical tests and clinical trials.

Keywords: CAR macrophage therapy, CAR-macrophage therapy development

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